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Toosendanin

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  Post Date: Oct 18,2013
  Expiry Date: Oct 18,2014
  Detailed Description: Cas No. :79304-40-8 Quantity: 100Metric Tons
Specs:1.5％,25%,98% (HPLC)，
Price:2231 USD Metric Tons
Payment Method: tt
Toosendanin

[Product name]: Toosendanin
[Plant Source]: CORTEX MELIAE
[Chemical name]: 1-isothiocyanato-4-(methyl-sulfinyl) butane
[Structural formula]: C30H38O11
[CAS Reg]: 79304-40-8
[Molecular weight]: 574.63
[Specification]: Toosendanin assay: 1.5％,25%,98% (HPLC)，or custom-made according to the customer request
[Main functions]:
Toosendanin (TSN), a tetranortriterpenoid compound from the plant Melia toosendan, has been reported to protect rats and non-human primates from the lethal actions of botulinum neurotoxin A (BoNT/A). TSN was tested in isolated mouse phrenic nerve-hemidiaphragm preparations against BoNT serotypes A, B and E. When added prior to toxin, TSN was found to delay the onset of muscle paralysis with all 3 BoNT serotypes. TSN had little or no effect on BoNT-induced muscle paralysis when applied 30 min after BoNT. It is suggested that the antagonist activity of TSN may result from inhibition of BoNT translocation

  CAS Registry Number:

79304-40-8
  Synonyms: 28-Deacetylsendanin; Chuanliansu;(1S,3R,4aR,6R,6aS,6bS,7aR,9R,9aR,10R,11aR,11bS,14R)-9-(furan-3-yl)-1,6,14-trihydroxy-4,6a,9a-trimethyl-11-oxotetradecahydro-1H-4,11b-(methanooxymethano)naphtho[1',2':6,7]indeno[1,7a-b]oxirene-3,10-diyl diacetate;(1S,4R,4aR,6R,6aS,6bS,7aR,9R,9aR,10R,11aR,11bS,14S)-9-(furan-3-yl)-1,6,14-trihydroxy-4,6a,9a-trimethyl-11-oxotetradecahydro-1H-4,11b-(methanooxymethano)naphtho[1',2':6,7]indeno[1,7a-b]oxirene-3,10-diyl diacetate;
  Molecular Formula: C30H38O11
  Molecular Weight: 574.62
  Molecular Structure: 79304-40-8 Toosendanin

  Company: hangzhou lingeba technology co.ltd     [ China ]        
  Contact: john
  Tel: 0571-87389059
  Fax: 0571-87389060
  Email: info@lingeba.com
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