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Calcitriol CAS No 32222-06-3
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| Post Date: | Dec 12,2016 |
| Expiry Date: | Dec 12,2017 |
| Detailed Description: |
Calcitriol
Detailed Information: Name 1α,25-Dihydroxyvitamin D3 CAS No 32222-06-3 Synonym Calcitriol 1,25-Dihydroxycholecalciferol Molecular Weight 416.64 M.F: C27H44O3 Purity 99%min Mp 119℃ MDL Number MFCD00867079 EINECS No 250-963-8 Appearance White powder Medicine Grade USP Grade Standard Medical stand Model Number API Model Number API Documents available COA,MSDS,NMR,HPLC Certificate SGS Usage Pharmaceuticals Molecular Weight 416.64 Packing 100mg,1g,5g,25g,100g/bottle Place of origin China Safety Description S36/37/39/S45 storage Store at -20° C,in N2, Keep from light. Description: Calcitriol is a metabolite of the secosteroid vitamin D3. This hormone stimulates intestinal calcium transport at a much higher rate than vitamin D3 and hydroxy D3, and is considered to represent the biologically active form of vitamin D3. In addition to regulating the movement of calcium in the blood and bone, 1α,25-Dihydroxyvitamin D3 participates in developmental regulation and signaling. It stimulates an increase in protein kinase C levels with an effect on the regulation of c-myc transcription and activation of Raf kinase. 1α,25-Dihydroxyvitamin D3 is shown to increase the synthesis of prostacyclin with a correlated increase in cyclooxygenase activity, indicating a further role in vascular regulation. 1α,25-Dihydroxyvitamin D3 (Calcitriol) is an activator of PKC and VDR. Appearance White or almost white crystals Conform Solubility Practically insoluble in water, freely soluble in alcohol, soluble in fatty oils Conform Identification Infrared spectrum corresponds to that of the standard preparation Conform The retention time of the major peak in the chromatogram corresponds to that in the chromatogram of standard preparation Conform Related Compounds Trazoline adduct of pre-calcitriol:NMT 0.5% ND Trans-calcitriol: NMT 0.5% 0.17% 1β-Calcitriol: NMT 0.5% ND Any other individual impurity: NMT 0.1% Conform Total impurities: NMT 0.1% 0.28% Purity NLT 99.0% 99.72% Loss on Drying NMT 0.5% <0.05% Heavy Metals NMT 20ppm Conform Residue on Ignition NMT 0.1% <0.05% Assay 97.0~103.0% 99.5% Application: 1. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. 2. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity 3. Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells Features : 1.Any inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. OEM/ODM Available. 5. Reasonable & competitive price, fast lead time. 6. Sample is available for your evaluation & Formulation development. 7. Faster delivery:Sample order in stock and 3-7 days for bulk production. 8. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder. 9. After-Sale Service: International Authorized Third-Party Test For The Products You Demand. Contact : If you have any further questions or need a sample,Please do not hesitate to contact us. ShenZhen Dieckmann Technology Development Co., LTD ShenZhen Address:2floor,3 building, Maluan Make Place,2-10south of Jinlong Road, Pingshan New district,Shenzhen Zip code: 518172 Tel: 86-755-89213952 Fax: 86-755-84813563 Email: sale@dkmchem.com |
| Company: | Shenzhen Dieckmann Technology Co.,Ltd [ China ] |
| Contact: | nancy |
| Tel: | 86-755-89213952 |
| Fax: | 86-755-84813563 |
| Email: | sale@dkmchem.com |
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